3-Amino-4,4,4-trifluorobutanoic acid

3-Amino-4,4,4-trifluorobutanoic acid - Names and Identifiers

Name	3-Amino-4,4,4-trifluorobutyric acid
Synonyms	4,4,4-trifluoro-β-homoalanine 4,4,4-TRIFLUORO-BETA-HOMOALANINE 3-AMINO-4,4,4-TRIFLUOROBUTYRIC ACID 3-Amino-4,4,4-trifluorobutyric acid 3-Amino-4,4,4-trifluorobutanoic acid 3-AMINO-4,4,4-TRIFLUOROBUTANOIC ACID DL-3-Amino-4,4,4-trifluorobutyric acid (3S)-3-ammonio-4,4,4-trifluorobutanoate (3R)-3-ammonio-4,4,4-trifluorobutanoate Butanoic acid, 3-amino-4,4,4-trifluoro-
CAS	584-20-3
InChI	InChI=1/C4H6F3NO2/c5-4(6,7)2(8)1-3(9)10/h2H,1,8H2,(H,9,10)/t2-/m0/s1

3-Amino-4,4,4-trifluorobutanoic acid - Physico-chemical Properties

Molecular Formula	C4H6F3NO2
Molar Mass	157.09
Density	1.3293 (estimate)
Melting Point	180-182°C(lit.)
Boling Point	238.3±40.0 °C(Predicted)
Flash Point	97.9°C
Vapor Presure	0.0145mmHg at 25°C
BRN	1764276
pKa	pK2: 5.831(0) (25°C)
Storage Condition	Room Temprature
Refractive Index	1.391
MDL	MFCD00041413

3-Amino-4,4,4-trifluorobutanoic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3
HS Code	29224985
Hazard Class	IRRITANT

3-Amino-4,4,4-trifluorobutanoic acid - Introduction

3-Amino-4,4,4-trifluorobutyric acid is an organic compound with the chemical formula C4H6F3NO2. The following is a description of its nature, use, formulation and safety information:

Nature:
1. Appearance: Colorless crystalline solid.
2. solubility: soluble in water and common organic solvents.
3. melting point: about 130-132 degrees Celsius.
4. It is an unstable compound and easily decomposed.

Use:
1. Pharmaceutical field: as an intermediate of synthetic drugs and biological drugs, it has anti-inflammatory, antibacterial, anti-cancer and other activities. In the process of drug development and manufacturing, it can be used to synthesize various drug molecular scaffolds.
2. chemical research: can be used as a reagent for organic synthesis and catalytic reactions.

Preparation Method:
The preparation of 3-Amino-4,4,4-trifluorobutyric acid is mainly carried out by chemical synthesis methods. One common method is to react 3-aminopropionic acid with trifluoroacetic anhydride to give the desired product.

Safety Information:
1. 3-Amino-4,4,4-trifluorobutyric acid is a chemical and needs to be handled in accordance with laboratory operating regulations.
2. avoid contact with eyes, skin and clothing. In case of accidental contact, rinse immediately with plenty of water.
3. During use, appropriate personal protective equipment should be worn, such as laboratory gloves, protective glasses and protective masks.
4. When storing and handling, please follow the relevant safety instructions.
5. If ingested or inhaled, seek medical attention immediately.

Last Update：2024-04-09 02:00:47